![]() |
研究及教育大楼 CB 3528
Office 手机图标: 706-721-0999
Lab 手机图标: 706-721-9860
实验室成员 |
Intracellular trafficking, signal regulation and patho-physiological functions of G protein-coupled receptors and G proteins.
1995 -1998 Post-Doctoral Fellowship Medical University of South Carolina
1992 Ph.D in Physiology Peking Union Medical College
and Chinese Academy of Medical Sciences, China
1988 M.S. in Biochemistry Xuzhou Medical College,
China
1983 B.S. in Biochemistry Beijing Normal University,
China
2011 - Present 教授 (with Tenure), Department of Pharmacology and Toxicology, MCG, 奥古斯塔大学, Augusta, GA.
2001 - 2011 Assistant/Associate 教授, Department of Pharmacology and Experimental Therapeutics, Louisiana State
University 健康 Sciences Center New Orleans, LA.
1999 - 2001 Assistant 教授, Department of Internal Medicine, University of Cincinnati, OH
生物科学前沿-里程碑
神经科学前沿
iScience
《公共科学图书馆•综合》
卡特, Bryant CN and Wu G. Gbgtranslocation to the Golgi apparatus activates ARF1 to spatiotemporally regulate G protein-coupled receptor signaling to MAPK. 生物化学 296:100805 (2021)
卡特, Wei Z, Xu X, Huang W, Lokeshwar BL, Lambert NA and Wu G. G protein bg translocation to the Golgi apparatus activates MAPK via PI3Kg. 生物化学 296:100325 (2021)
Wei Z, Xu X, Fang Y, 卡特, 诺顿 SX, Hu G, 小特里AV and Wu G. Rab43 GTPase directs post-synaptic trafficking and neuron-specific sorting of G protein-coupled receptors. 生物化学 296:100517 (2021)
Fang Y, Jiang Q, Li S, Zhu H, Xu R, Song N, Ding X, Liu J, Chen M, Song M, Ding J, Lu M, Wu G and Hu G. Opposing functions of β-arrestin1 and 2 in Parkinson’s disease via microglia inflammation and Nprl3. 细胞死亡不同 28 (6): 1822 - 1836 (2021)
Zhang M, Xu X, Li C, Huang W, Xu N, and Wu G. A naturally occurring splice variant of GGA1 inhibits the anterograde post-Golgi traffic of a2 b-adrenergic receptor. Sci代表 9:10378 (2019)
Wei Z, Zhang M, Li C, Huang W, Fan Y, Guo J, 卡特, Fukuda M, Dong Z, Hu G and Wu G. Specific TBC domain-containing proteins control the ER-Golgi-plasma membrane trafficking of GPCRs. 细胞代表 28 (2): 554 - 566 (2019)
Li ZW, Sun B, Gong T, Guo S, Zhang J, Wang J, Sugawara A, Jiang M, Yan J, Gurary A, Zheng X, Gao B, Xiao SY, Chen W, Ma C, Farrar C, Zhu C, Chan OTM, Xin C, Winnicki A, Winnicki J, Tang M, Park R, Winnicki M, Diener K, Wang Z, Liu Q, Chu CH, Arter ZL, Yue P, Alpert L, Hui GS, Fei P, Turkson J, Yang W, Wu G, Tao A, Ramos JW, Moisyadi S, Holcombe RF, Jia W, Birnbaumer L, Zhou X and Chu WM. GNAI1 and GNAI3 reduce colitis-associated tumorigenesis in mice by blocking IL6 signaling and downregulating expression of GNAI. 胃肠病学 156 (8): 2297 - 2312 (2019)
Li C, Wei Z, Fan Y, Huang W, Su Y, Li H, Dong Z, Fukuda M, Khater M and Wu G. The GTPase Rab43 controls the anterograde ER-Golgi trafficking and sorting of GPCRs. 细胞代表 (4): 1089 - 1101 (2017)
Zhang M, Huang W, Gao J, Terry AV Jr and Wu G. Regulation of α2 b-adrenergic receptor cell surface transport by GGA1 and GGA2. Sci代表 6:37921 (2016)
Zhang M, Davis JE, Li C, Gao J, Huang W, Lambert NA, 小特里AV and Wu G. GGA3 interacts with a G protein-coupled receptor and modulates its cell surface export. Mol细胞生物学 36 (7): 1152 - 1163 (2016)